Following the American College of Rheumatology (ACR), the presence of anti-dsDNA antibodies is one of the diagnostic criteria for Systemic Lupus Erythematosus (SLE). Indeed, they are reported to have a high pathogenic and diagnostic significance for SLE.
They are among the most frequently detected autoantibodies associated with SLE. Moreover the dsDNA antibody titer usually correlates with disease activity and dsDNA antibodies are therefore classified as markers of SLE activity.
dsDNA purified from bovine thymus (for more information on our antigens click here)